Solvias AG

Solvias is a privately held company located in Basel, Switzerland, with over 280 highly qualified employees.

We support the research and development of drug substances and the optimization of manufacturing processes for pharmaceutical, biotechnology and life sciences companies worldwide.

Solvias customers benefit from a wide range of experience in the following areas:

Catalysis Development Services

Lead finding through high-quality screening, catalysis development and ligand/ catalyst offerings. Solvias also has a broad expertise in asymmetric hydrogenation and achiral heterogeneous hydrogenation.

• HTS-Screening
• Catalysis Development Services
• Solvias Ligands and Catalysis Products
• Asymmetric Hydrogenation
• CX-Coupling
• Heterogenous Hydrogenation

API Chemical Development

Full package of chemical and analytical services along the API Chemical Development Process from discovery to production:

• Lead Synthesis / Custom Synthesis
• Process Research and Development
• Kilogram Scale Synthesis
• API Synthesis
• High Pressure Chemistry (Hydrogenation, Carbonylation, Amination)
• Hazardous Chemistry (Fluorination, Phosgenation)

Polymorphism, Salt and Co-Crystal Screening

Comprehensive physical chemistry services for the identification and selection of polymorphs, salts, and co-crystals, including method development for polymorphic purity and the optimization of crystallization processes:

• Polymorphism
• Solid Form Screening and Selection
• Crystallization
• Method Development and Validation
• Quality Control of Drug Substances and Drug Product
• Support of Troubleshooting
• Salt Screening and Characterization
• Co-Crystal Screening

Analytical Services

Solvias offers Analytical services such as method development, validation and release testing with a broad technology base:

• Highly Active and Highly Toxic Substances
• Analytical Characterization
• Method Development and Validation
• Quality Control Analysis
• Stability Studies
• Leachables and Extractables
• Reference Substances
• Elemental Analysis
• Microbiology
• Environmental Analysis
• Manufacturing Support

Biopharmaceutical Analysis

Biopharmaceutical analysis services for protein-based drugs to biotechnology and pharmaceutical companies at every stage of drug development:

• Characterization Programs
• Method Development and Validation           
• Release Testing
• Stability Studies
• CE-Technologies
• Nuclein Acid Analysis
• PCR Technology

Process Analytical Technology / PAT

Delivering comprehensive Process Analytical Technology for continuous monitoring of your chemical production and formulation processes:

• Fiber-optic Probes
• Liquid transmission Flow Cells / Immersion Probes
• Gas transmission Flow Cells
• Diffuse Reflectance Immersion Probes
• Transflection Immersion Probes
• ATR Immersion Probes
• Process Analytical Solutions