SubscribeApplications and developments in ultrasonic process chemistry
Partner with Prosonix for:
- Complete Crystallization Control™
- Commercial scale sonocrystallization
- Prosonitron™ reactor technology
- Award winning CrystalGEM™ predictive crystallization technology
- Sonobiocatalysis™
- Sonochemistry
NEW for CPhI Worldwide
- SAX™ particle engineering technology
Power ultrasound causes cavitation
Controlled cavitation allows controlled nucleation
Case study: Late stage innovator API
- Single point brief insonation at 'low' supersaturation
- Multi-point brief insonation with cooling starting at 'low' supersaturation
- Similar to 2. but with increased stirrer speed
- Similar to 2. and 3. but with delayed insonation at 'medium' supersaturation
Key results: reduced median crystal size, tighter CSD and morphological control Case study: Late stage innovator API
Commercial scale sonocrystallization
Proprietary process technology
Prosonitron™ reactor technology
- Sonocrystallization,sonoprocessing and sonochemistry
- Ultrasonic wet milling
- Proprietary design allows 100% ofprocess volume to be insonated
- Typical power densities 5-80 WL-1
- Cavitation blocking eliminated
- Can be fabricated in a range ofmaterials
- Eliminates the historic problems associated with ultra-sonic probes
- ATEX approved design
- Proprietary ultrasonic flow cell
- Modular design for optimum flexibility
- No erosion or shedding
- GMP compliant
- ATEX certified
- Low power
- Sustainable green technology
