SubscribeThe optimum crystallization screening methodology for pharmaceuticals
- Highly cost effective, rational approach
- Rapid response service
- Generates 100% useful information on:
- habit, morphology, polymorphs, solvates
- Outcome and scale-up focused
- Reduces time to market
E.g. Indomethacin: CrystalGEM™ viable conditions Prediction
The Rational Screening of Crystallizations for Pharmaceutical Products through Pattern Recognition
- Winner of the CPhI 2005 Gold Innovation Award
- Structurally and outcome driven
- Uses proprietary pattern recognition technology and QSAR analysis
- Predicts probability and feasibility of morphology and polymorphism in-silico
- Predicts optimum solvent conditions for desired outcome
- Draws on an in-house database of over 15,000 real experimental conditions
- Proprietary microcrystallization technique confirms prediction with only mg quantities of compound
CrystalGEM™
- Can be applied at any stage during development
- Significantly reduces time and cost of crystallization screening
- Results can be directly used by the industrial user
- Makes traditional high throughput crystallization screening obsolete